Queensland Police  are appealing for public assistance to help locate a 15-year-old reported missing from Caboolture on December 29, 2015.

Jesse Vernon-Ware was last seen by family when he left a Toohey Street residential address in Caboolture.

He was last sighted on January 4 at a shopping centre in Caboolture.

Police and family are concerned for his welfare as he suffers from a medical condition.

Jesse is described as Aboriginal in appearance, 160cm tall with a heavy build, weighs 75kg, and has dark brown hair.

It is believed Jesse is wearing a blue baseball cap, and could be wearing a blue T-shirt and gold-coloured running shoes.

If anyone has any knowledge as to the whereabouts of Jesse, they are encouraged to contact Crime Stoppers on 1800 333 000.